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Quickmice™ Tlhōlisano ea Mouse e potlakileng ea KI

quicktomice-fast-ki-mouse-customization-sehlahisoa

Knock-in (Knock-in, KI) ke mokhoa o sebelisang motsoako oa homologous oa liphatsa tsa lefutso ho fetisetsa gene e sebetsang ka mokhoa o ts'oanang ka tatellano ea homologous ka sele le genome, le ho fumana polelo hantle ka seleng ka mor'a ho kopanya liphatsa tsa lefutso.

Ho nka likhoeli tse 5-6 ho fumana litoeba tsa heterozygous tse hlakotsoeng le kakaretso ea likhoeli tse 10-12 ho haha ​​​​moetso oa litoeba tsa KI homozygous ka litekanyetso tse tlase tsa katleho ho sebelisa mekhoa ea setso, hobane mekhoa ena e na le chimera positivity e tlaase 'me e hloka ho nyalana le mouse. fumana litoeba tse hlakotsoeng tsa heterozygous, ebe o tsoalisa litoeba tse tsoetsoeng tsa heterozygous bakeng sa meloko e 2-3 ho fumana litoeba tsa KI homozygous.

Moloko o Mocha oa Rapid Mouse Preparation Technology

TurboMice™

Re ka u fa kapele mefuta ea litoeba tsa KI homozygous ka ho sebelisa theknoloji ea TurboMice™ ho ntlafatsa sekhahla sa katleho.

Ho ipapisitsoe le lenaneo le nepahetseng la ho fetola liphatsa tsa lefutso ke bo-ramahlale ba rona, re ka phethela tlhahlobo ea lisele tsa embryonic tse hlophisitsoeng nakong ea matsatsi a 3-5, ebe re theha embryo ea tetraploid.Ka mor'a ho surrogacy, litoeba tsa homozygous humanized li ka fumanoa nakong ea likhoeli tse 2-4, tse ka bolokang likhoeli tse 7-8 bakeng sa bareki.

Litaba tsa Tšebeletso

Tšebeletso No. Li-index tsa tekheniki Likahare tsa thomello Potoloho ea thomello
MC002-1 bolelele ba lefutso le le leng <5kb 3-9 KI homozygous litoeba tse tona Likhoeli tse 2-4
MC002-2 bolelele ba lefutso le le leng <5kb 10-19 KI homozygous litoeba tse tona Likhoeli tse 2-4
MC002-3 bolelele ba lefutso le le leng <5kb 20 KI homozygous litoeba tse tona 3-5 likhoeli
MC002-4 bolelele ba lefutso le le leng ke 5kb-10kb 3-9 KI homozygous litoeba tse tona 3-4 likhoeli
MC002-5 bolelele ba lefutso le le leng ke 5kb-10kb 10-19 KI homozygous litoeba tse tona 3-4 likhoeli
MC002-6 bolelele ba lefutso le le leng ke 5kb-10kb 20 KI homozygous litoeba tse tona 3-5 likhoeli

Iteanye le rona

Ka kopo ikopanye le rona ho:

1) Ka kopo, khoasolla le ho tlatsa foromo e ka tlase《Foromo ea Kopo ea Khoutu》, 'me u e romelle ka lengolo-tsoibila hoMingCelerOversea@mingceler.com;

2) Te: +86 181 3873 9432;

3) LinkedIn: https://www.linkedin.com/company/ molaor/

Foromo ea Kopo ea Khoutu.docx

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